IPOs

How the Largest IPO of 2025 Could Be Healthy for Your Portfolio

Did you know that the largest initial public offering in 2025 was a boring medical supply company based in Chicago? But, boring can be beautiful, and Medline (MDLN) looks primed and ready to continue delivering on its history of rapid, profitable sales growth.

Medline bills itself as “the largest provider of medical-surgical products and supply chain solutions serving all points of care.” It boasts 335,00 products and 33 manufacturing facilities in more than 100 countries. 95% of customers here in the United States can receive next-day delivery. It therefore isn’t much of an exaggeration to consider Medline the Amazon (AMZN) of medical and surgical (“medsurg”) products.

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Hospitals, surgery center, and physicians are among the main users of Medline’s medical kits, surgical gloves, wound care, and lab supplies. A key competitive advantage is its namesake Medline Brand products, which count as private label and help boost margins. By serving as both the manufacturer and distributor, it gets to keep the margin another reseller might demand to get its products to market.

Medline just went public, but was already publicly traded prior to a private buyout back in 2021. The buyout at the time was for $34 billion. The current initial public offering (IPO) was priced at $29 per share and raised $6.3 billion, which will be used to pay down debt. Medline’s current valuation is $35.5 billion, or only slightly ahead of the valuation at which it was taken private. Based on the valuation multiple of EV/EBITDA, both the buyout and IPO are in the mid-teens.

So, what the heck did the private equity buyers, which included Blackstone, Carlyle, and Hellman & Friedman, do while Medline was privately owned? They grew sales substantially. At the time of the buyout , Medline reported 20 manufacturing sites, which has increased by over 50% to 33. And sales were $17.5 billion in 2020. Current analyst projections call for around $30 billion in sales this year (full year 2026).

Debt during the buyout in 2021 was $17 billion, or half of the $34 billion. This heavy debt load was cited as motivation to raise capital during the IPO. Debt stood at $16.5 billion prior to the IPO. We’ll see during the next earnings release the extent to which debt has been paid down. Analysts are already pretty optimistic that this is taking place.

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